SpaceX launched its mega rocket Starship but lost both the booster and spacecraft minutes into the test flight.
The rocketship reached space, but communication was lost eight minutes after liftoff Saturday from South Texas.
SpaceX declared that the vehicle had failed.
The trouble cropped up as the ship's engines were almost done firing to put it on an around-the-world path.
Minutes earlier, the booster exploded over the Gulf of Mexico.
The first test flight in April ended in an explosion soon after liftoff.
At 400 feet, Starship is the biggest and most powerful rocket ever built.