The SIU is investigating a single vehicle crash overnight in St. Catharines.
Reports say two males in their twenties were taken to hospital with head injuries after the vehicle crashed into a concrete wall.
It happened overnight on Fourth Ave at Highway 406.
Both males were airlifted to hospital.
One to Hamilton General and the other to St. Mikes Hospital in Toronto.
According to the NRP website, the area is still closed to traffic as of 11:30 a.m.